The report ‘Time to End Prohibition’ marks the 10th anniversary of the Global Commission on Drugs. Ten years after the establishment of the Global Commission, the taboo on drugs has been well and truly broken. In the last decade, there were impressive reforms around the world at national and sub-national levels. More and more countries are decriminalizing drug use, adopting innovative approaches based on public health, and legalizing formerly banned substances.

In this first report of the decade, the Global Commission on Drug Policy outlines how the current international drug control regime works for the benefit of transnational organized crime. It highlights how years of repressive policies targeted at nonviolent drug offenders have resulted in mass incarceration and produced countless adverse impacts on public health, the rule of law, and social cohesion.

This report exposes how the biased historical classification of psychoactive substances has contributed to the "world drug problem". It is the first-ever comprehensive report providing a political reading of the current evaluation and classification of drugs according to their harms.